Item #CRD01
Dr. Stephen Sinatra
CardioSense Probiotic
3-in-1 next-generation probiotic for better digestive, heart, and immune health!






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Additional Product Details
3-in-1 next generation
probiotic for digestive, heart, and immune support
Digestive Support
Heart Support
Immune Support
Cardiologist Formulated


Clinically Validated TriBiotic Probiotic Blend
This innovative probiotic delivers 12 billion CFU of robust benefits in a unique TriBiotic Probiotic Blend plus three Bifidobacteria strains to deliver clinically validated digestive, heart, and immune benefits.
Each dose delivers all this using stay-fresh innovative technology to keep you feeling your best. And you won’t find this probiotic combination anywhere else!

Comprehensive Digestive Support
The Floradapt Intensive GI strain was shown in a clinical study to be hardy against the acidic environment of the stomach and intestines and was shown in multiple studies to support the digestive system and digestive comfort.*,** You also get a Bifido blend of 3 strains that provide support for your lower intestine, giving you complete digestive support.
*Lorenzo-Zuniga V, et al. World J Gastroenterol. 2014 Jul 14;20(26):8709–16.
**Barraza-Ortiz DA, et al. Dig Dis. 2021;39(3):294–300.

HUGE heart benefits
The Floradapt Cardio blend delivers a combination of three Lactobacillus plantarum strains that have been clinically validated to provide excellent support for overall heart support benefiting total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides and lipid oxidation.*,**
*Fuentes M, et al. Br J Nutr. 2012 May 28;109(10):1866–72.
**Fuentes M, et al. Mediterranean J of Nutr & Metabolism. 2016;9(2):125–35.

Robust immune support!
Since so much of your digestive system lives in your gut, Dr. Sinatra included robust Floradapt Mature Immune Defense, which was specifically studied in older adults and found to support the adaptive immune system—the part of our immune response that changes the most as we age. It also supports immune function and immune system cells.*
*Mane J, et al. Nutr Hosp. 2011;26(1):228–35.
Innovative bottle technology for moisture protection and enhanced stability
CardioSense Probiotic is bottled with technology that helps protect the probiotic from moisture. This ultimately helps provide enhanced stability and ensures efficacy. And, helps deliver a long shelf life of 24 months. Plus, no refrigeration is necessary!


Vegetarian capsules release the probiotics exactly when and where you need them
CardioSense Probiotic was made using innovative Capsugel Vcaps Plus Capsules that are vegetarian and dissolve quickly using immediate-release technology. They also feature a lower moisture content and sensitivity, making them less brittle and less likely to break.

Floradapt Intensive GI + Bifido Blend
Remarkable digestive support starts with Floradapt Intensive GI. In one clinical study, 38% of participants experienced improvement in abdominal discomfort and over 44% experienced improvement in stool consistency.*,** Benefits included improved regularity, better stool consistency, and digestive comfort support. Plus, it was shown to reduce occasional diarrhea, control occasional gas and flatulence, and support abdominal calm in those with GI concerns after lactose intake.***
*Lorenzo-Zuniga V, et al. World J Gastroenterol. 2014 Jul 14;20(26):8709–16.
**Barraza-Ortiz DA, et al. Dig Dis. 2021;39(3):294–300.
***Cano-Contreras A.D, et al. J Clin Gasteroenterol. 2020;0(0):1 -7.

Heart Blend Floradapt Cardio
The Floradapt Cardio blend features a combination of three Lactobacillus plantarum strains that have been clinically validated*,** to provide excellent lipid metabolism and overall heart support, to help benefit levels of total cholesterol and LDL cholesterol, triglycerides, lipid oxidation, and levels of HDL cholesterol.
*Fuentes M, et al. Br J Nutr. 2012 May 28;109(10):1866–72.
**Fuentes M, et al. Mediterranean J of Nutr & Metabolism. 2016;9(2):125–35.

Impressive immune benefits
The unique dual-strain blend Floradapt Mature Immune Defense strain was specifically studied in an older population and found to support and benefit immune response and immune function, levels of immune system cells, and levels of IgA, a key immune factor in supporting mucous membranes.* In addition, this strain also supports C-Reactive Protein**,***, a critical marker of how your body responds to inflammation.
*Mane J, et al. Nutr Hosp. 2011;26(1):228 -35.
**Bosch M, et al. Nutr Hosp. 2012;27(2):504–9.
***Bosch Gallego M, et al. Nutr Hosp. 2011;26(3):642–45.
Formulated by Integrative Cardiologist Stephen Sinatra, M.D.
A true pioneer, Dr. Sinatra spent more than 40 years in clinical practice, including serving as an attending physician and chief of cardiology at Manchester Memorial Hospital, then going on to formulate his advanced line of heart health supplements. His integrative approach to heart health has changed the lives of hundreds of thousands.

Ingredients and Dosage
Doctor’s Suggested Use: Mix 1 packet with 6–10 fluid ounces of water, depending upon your flavor intensity preference. Stir or shake until powder dissolves and consume. Take 1–2 packets daily as needed.
Serving Size: 1 Packet (9.4 g)
Servings Per Container: 30
Ingredient | Amount Per Serving | % DV |
Calories | 20 | |
Total Carbohydrate | 5 g | 2%* |
Total Sugars | 5 g | ‡ |
Includes 5g Added Sugars | 10%* | |
Vitamin C (as ascorbic acid) | 1,000 mg | 1,111% |
Vitamin D (as cholecalciferol) | 25 mcg (1,000 IU) | 125% |
Vitamin B6 (as pyridoxine HCl) | 10 mg | 588% |
Folate (as (6s)-5-methyltetrahydrofolic acid glucosamine salt) | 165 mcg DFE | 41% |
Vitamin B12 (as methylcobalamin) | 25 mcg | 1,042% |
Magnesium (as magnesium citrate) | 100 mg | 24% |
Zinc (as zinc oxide) | 5 mg | 45% |
Selenium (as selenomethionine) | 25 mcg | 45% |
Manganese (as manganese sulfate) | 0.5 mg | 22% |
Chromium (as chromium polynicotinate) | 50 mcg | 143% |
Potassium (as potassium carbonate, potassium phosphate, potassium bicarbonate) | 500 mg | 11% |
Antioxidant Blend: Red Grape Skin Extract, Grape Seed Extract | 100 mg | ‡ |
Seaweed-Derived Trace Mineral Blend (Aquamin®) | 10 mg | ‡ |
Vanadium (as vanadyl sulfate) | 50 mcg | ‡ |
Stevia Extract (leaf) | 30 mg | ‡ |
* Percent Daily Values are based on a 2,000 calorie diet. ‡ Daily Value (DV) not established |
Other ingredients: Cane sugar, citric acid, malic acid, natural flavors, silica, steviol glycosides
Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.
Keep out of reach of children.
Science and Quality
Like all of Dr. Sinatra’s formulas, Cardio Immune Support meets stringent requirements for both potency and purity—and has gone through dozens of quality and safety checks at every point, from raw ingredients to the finished product.
Cardio Immune Support is produced in accordance with our strict Standard Operating Procedures (SOPs) that meet or exceed those set by the FDA’s Good Manufacturing Practices. And quality is assured with our Triple-Testing Philosophy and backed by a 100% satisfaction guarantee.
Vitamin C for immune health and more
Vitamin C is a vital nutrient for the immune system and is also an indispensable antioxidant. The body uses it as a cofactor in multiple enzymatic reactions, Therefore, its benefits extend far beyond the immune system.
An electrolyte overview
Electrolytes must be in balance in the human body for normal cellular and organ function. Three major positively charged electrolytes are sodium, potassium, and magnesium.
Sodium and potassium balancing
Sodium is one of the most important electrolytes, being the ion found in the fluid outside of the cell. Most people get plenty of sodium in the diet, which is important for maintaining the proper amount of water in the body. However, too much sodium is associated with high blood volume, which increases blood pressure levels, so we make it a point not to include it in this formula.
Balancing sodium intake with potassium is critical because it is the main electrolyte found inside the fluid of the cells. Recommended daily intake for potassium is quite high (3,500 mg), and often difficult to obtain.
Depletion of electrolytes
Electrolytes can be depleted from the body by a variety of causes including excessive sweating from exercise, diarrhea, vomiting, and medications, including cardiovascular medications like diuretics, certain antibiotics, gout drugs, antacids, and anti-inflammatories like prednisone and aspirin.
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